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Resveratrol, SIRT1 and anti-aging

14 February, 2012

We have already learned that resveratrol, an extract derived from plant material, is a great antioxidant.  When resveratrol is in the body, it works to neutralize free radicals—rogue oxygen molecules that can damage or weaken cells. Free radicals can cause visible signs of aging, such as facial wrinkles, as well as injuries to the body’s internal structures, including damage to tissues or blood vessels.

How is resveratrol different from other antioxidants? Recent studies have indicated that resveratrol may prevent cells from overexerting themselves. Resveratrol turns on the SIRT1 protein, which controls the activation of genes.

Not all of the information encoded on our genes is “turned on,” or expressed, at the same time. Some genes react to the stresses of internal or external factors, including:

  • Bacteria or viruses
  • Inflammation
  • Toxins
  • UV radiation (from sunlight or X rays)

But as we age, sometimes the on/off calibration switch of our genes can be affected. The “overuse” of the functions controlled by the genes may damage the cell.

While the SIRT1 protein usually acts as a sentry to prevent the genes from being activated unnecessarily, it also can help repair damaged DNA. Healthy cells that are properly regulated at all levels (down to the genetic material) are the foundation of a healthy body.

Adding resveratrol to your self-care routine introduces a concentrated boost of this powerful antioxidant. When resveratrol controls the SIRT1 protein, the body’s cells should healthfully self-regulate and even begin to repair themselves.

 
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